Post‐transplant lymphoproliferative disorders are not associated with IgG4 sclerosing disease
Identifieur interne : 004759 ( Main/Exploration ); précédent : 004758; suivant : 004760Post‐transplant lymphoproliferative disorders are not associated with IgG4 sclerosing disease
Auteurs : H. P. Cathro [États-Unis] ; G. C. Bullock [États-Unis] ; H. Bonatti [États-Unis] ; Z. Meriden [États-Unis] ; S. Cook [États-Unis] ; N. Aguilera [États-Unis]Source :
- Transplant Infectious Disease [ 1398-2273 ] ; 2014-12.
Abstract
Although the majority of post‐transplant lymphoproliferative disorder (PTLD) cases are associated with Epstein–Barr virus (EBV), 20–42% of cases are EBV negative (EBV‐N). The antigenic stimulus that drives EBV‐N PTLD is unknown, but is likely heterogeneous. A common feature of PTLD, regardless of EBV status, is an abnormal polytypic lymphoplasmacytic infiltrate. Immunglobulin‐G4 (IgG4) syndrome is also characterized by a polytypic lymphoplasmacytic infiltrate with a predominance of IgG4‐positive (IgG4‐P) plasma cells.
Url:
DOI: 10.1111/tid.12300
Affiliations:
- États-Unis
- Maryland, Pennsylvanie
- Baltimore, College Park (Maryland), Pittsburgh
- Université de Pittsburgh, Université du Maryland
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